HEATR3 recognizes membrane rupture and facilitates xenophagy in response to Salmonella invasion

AdminUncategorized1 month ago23 Views

Proceedings of the National Academy of Sciences, Volume 122, Issue 14, April 2025.
SignificanceThis study identifies HEATR3, a protein associated with Crohn’s disease and involved in the NOD2-mediated NF-κB inflammatory signaling pathway, as a receptor for selective autophagy. HEATR3 recognizes damaged membranes, facilitates the …
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