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Now Reading: ATM priming and end resection–coupled phosphorylation of MRE11 is important for fork protection and replication restart

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ATM priming and end resection–coupled phosphorylation of MRE11 is important for fork protection and replication restart

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ATM priming and end resection–coupled phosphorylation of MRE11 is important for fork protection and replication restart

AdminUncategorized1 month ago23 Views

Proceedings of the National Academy of Sciences, Volume 122, Issue 16, April 2025.
SignificanceThe MRE11/RAD50/NBS1 (MRN) complex plays multiple roles in the maintenance of genome stability, requiring coordinated regulation of its activities, though the underlying mechanisms are not fully understood. In this study, we identified …
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