Elevated brain manganese induces motor disease by upregulating the kynurenine pathway of tryptophan metabolism

IO_AdminUncategorized1 month ago26 Views

Proceedings of the National Academy of Sciences, Volume 122, Issue 16, April 2025.
SignificanceAccumulation of essential metals in the brain induces incurable neuromotor disease. Mechanisms are unknown, which has limited therapeutic development. Here, we focus on manganese-induced motor disease, which is a major public health problem…
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