Cryo-EM structure of the conjugation H-pilus reveals the cyclic nature of the TrhA pilin

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Proceedings of the National Academy of Sciences, Volume 122, Issue 16, April 2025.
SignificanceA major medical challenge is the spread of bacteria which are resistant to antibiotics. The resistance genes are spread via mobilized DNA, mainly via a process named conjugation. During conjugation, a resistant bacterium (donor…
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