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Now Reading: Accurate identification and mechanistic evaluation of pathogenic missense variants with Rhapsody-2

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Accurate identification and mechanistic evaluation of pathogenic missense variants with Rhapsody-2

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U.S.//Discover the latest updates from across the United States, including politics, culture, economy, and trending stories. Stay informed on the key events shaping the nation and the topics everyone’s talking about.
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Accurate identification and mechanistic evaluation of pathogenic missense variants with Rhapsody-2

kisded kisdedUncategorized2 weeks ago12 Views

Proceedings of the National Academy of Sciences, Volume 122, Issue 18, May 2025.
SignificanceUnderstanding the impact of single amino acid variants (SAVs) on protein function is pivotal for detecting and treating genetic disorders. We presentRhapsody-2,a machine learning tool that leverages AlphaFold2-predicted protein structures to …
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