Multiscale biased chemical space remodeling for developing APLNR agonists with anti-HFpEF efficacy

kisded kisdedUncategorized2 weeks ago14 Views

Proceedings of the National Academy of Sciences, Volume 122, Issue 18, May 2025.
SignificanceHeart failure with preserved ejection fraction (HFpEF) is a prevalent and complex syndrome that poses a significant therapeutic challenge due to its resistance to conventional pharmacotherapies. Our study addresses this unmet need by …
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