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Now Reading: Cyclic peptide inhibitors function as molecular glues to stabilize Gq/11 heterotrimers

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Cyclic peptide inhibitors function as molecular glues to stabilize Gq/11 heterotrimers

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Cyclic peptide inhibitors function as molecular glues to stabilize Gq/11 heterotrimers

AdminUncategorizedYesterday9 Views

Proceedings of the National Academy of Sciences, Volume 122, Issue 19, May 2025.
SignificanceHeterotrimeric G proteins act as molecular switches that control cellular responses to external signals. Small molecules that selectively inhibit these proteins are essential for studying their function and therapeutic potential. FR900359 (FR) …
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