Sex-chromosome complement and Activin-A shape the therapeutic potential of TNFR2 activation in a model of MS and CNP

Proceedings of the National Academy of Sciences, Volume 122, Issue 20, May 2025.
SignificanceThis study highlights the critical role of sex-chromosome complement and gonadal Activin-A in therapeutic efficacy of TNFR2 activation in alleviating motor deficits and chronic neuropathic pain (CNP) in a model of multiple sclerosis (MS…
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