Mutant IDH1 cooperates with NPM1c or FLT3ITD to drive distinct myeloid diseases and molecular outcomes

kisded kisdedUncategorized7 hours ago6 Views

Proceedings of the National Academy of Sciences, Volume 122, Issue 20, May 2025.
SignificanceOur work highlights the importance of investigating co-occurring driver mutations of a disease and provides a mouse model in whichIdh1mutation, in the presence of mutantNpm1c, is linked to the development of overt AML…
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