Novel Antiviral Targets Yellow Fever Virus Through NS4B Protein

Rapid Summary

• Yellow fever virus (YFV) continues to be endemic in 47 countries across South America and Africa.
• Despite the availability of an effective vaccine, millions of lives remain at risk due to the absence of an approved antiviral drug.

Indian Opinion Analysis
Yellow fever, while primarily affecting regions in South America and Africa, underscores a notable global health concern with wider implications for India. The country’s active engagement with global health challenges and partnerships could play a pivotal role in combating diseases like yellow fever through vaccine development support or research collaboration on antiviral treatments. As India strengthens its pharmaceutical sector’s contribution internationally, closer attention to emerging threats such as YFV can foster preparedness against transnational epidemics or outbreaks that could possibly affect travelers or expand geographically over time.

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