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Now Reading: CD83 suppresses endogenous March-I-dependent MHC class II ubiquitination, endocytosis, and degradation

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CD83 suppresses endogenous March-I-dependent MHC class II ubiquitination, endocytosis, and degradation

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CD83 suppresses endogenous March-I-dependent MHC class II ubiquitination, endocytosis, and degradation

AdminUncategorized2 days ago11 Views

Proceedings of the National Academy of Sciences, Volume 122, Issue 21, May 2025.
SignificanceAntigen-presenting cells (APCs) function by binding peptides generated from endocytosed antigens and expressing these peptides on the APC surface bound to MHC-class II (MHC-II) molecules. MHC-II has a relatively short lifetime on the surface …
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