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Now Reading: CRISPR screen reveals a simultaneous targeted mechanism to reduce cancer cell selenium and increase lipid oxidation to induce ferroptosis

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CRISPR screen reveals a simultaneous targeted mechanism to reduce cancer cell selenium and increase lipid oxidation to induce ferroptosis

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U.S.//Discover the latest updates from across the United States, including politics, culture, economy, and trending stories. Stay informed on the key events shaping the nation and the topics everyone’s talking about.
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Opinion//Transform your living spaces with inspiration, tips, and trends in interior design. From minimalist decor to bold statements, find ideas for every style and budget.
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CRISPR screen reveals a simultaneous targeted mechanism to reduce cancer cell selenium and increase lipid oxidation to induce ferroptosis

AdminUncategorizedYesterday10 Views

Proceedings of the National Academy of Sciences, Volume 122, Issue 22, June 2025.
SignificanceFerroptosis is an iron-dependent cell death mechanism that results from increased oxidation of cell membrane lipids. We conducted a CRISPR-based positive selection screen in clear cell ovarian cancer cells treated with a nanoparticle drug to …
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