Unexplained Kidney Disease Claims Lives of Thousands of Young Men

Quick Summary:

• Chronic Kidney Disease of unknown cause (CKDu) is affecting thousands worldwide,especially agricultural workers in sugar-cane-growing regions like Bajo Lempa,El Salvador.
• Teh disease targets young adults (20-50 years), frequently enough those exposed to intense labor in extreme heat. Causes remain unclear but suspected factors include dehydration, heat stress, pesticide exposure, and nephrotoxic medications.
• CKDu has spread globally to hotspots such as Nicaragua, Mexico, India, sri Lanka, and Nepal; high temperature workplaces are identified as major contributors.
• Climate change is anticipated to exacerbate kidney-related health challenges due to worsening global heat levels.
• In El Salvador’s Bajo Lempa district alone: 25% of adult men suffer general kidney disease; 17% face end-stage kidney failure with limited access to dialysis care due systemic health capacity limits

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