Energy landscape analysis of the development of the chromosome structure across the cell cycle

AdminUncategorized2 months ago23 Views

Proceedings of the National Academy of Sciences, Volume 122, Issue 12, March 2025.
SignificanceIn cell division, chromosomes change folds and assume different shapes during the cell cycle. We combined a maximum entropy approach with polymer physics to model an ensemble of 3D chromosomal structures consistent with Hi-C data during …
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