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Now Reading: Allosteric inhibition of the IZUMO1–JUNO fertilization complex by the naturally occurring antisperm antibody OBF13

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Allosteric inhibition of the IZUMO1–JUNO fertilization complex by the naturally occurring antisperm antibody OBF13

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Allosteric inhibition of the IZUMO1–JUNO fertilization complex by the naturally occurring antisperm antibody OBF13

IO_AdminUncategorized3 months ago33 Views

Proceedings of the National Academy of Sciences, Volume 122, Issue 10, March 2025.
SignificanceIn the United States, 9% of men and 11% of women of reproductive age experience fertility problems. Successful fertilization requires the proper recognition, adhesion, and fusion of sperm and an egg. Here, we show how a naturally occurring …
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