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Now Reading: Allosteric regulation of UBIAD1 trafficking from ER to Golgi revealed by chemical genetic screening

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Allosteric regulation of UBIAD1 trafficking from ER to Golgi revealed by chemical genetic screening

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Allosteric regulation of UBIAD1 trafficking from ER to Golgi revealed by chemical genetic screening

IO_AdminUncategorized3 days ago11 Views

Proceedings of the National Academy of Sciences, Volume 122, Issue 20, May 2025.
SignificanceMutations in the gene encoding UbiA prenyltransferase domain-containing protein-1 (UBIAD1) cause Schnyder corneal dystrophy (SCD), a rare genetic disorder marked by the abnormal accumulation of cholesterol in the cornea. These mutations …
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