Proceedings of the National Academy of Sciences, Volume 122, Issue 16, April 2025.
SignificanceMany important physiological processes are regulated by GPCR-mediated activation of Gqheterotrimers and PLCβ enzymes. Ion channels and other membrane proteins are regulated by PIP2 in the plasma membrane, and inositol 1,4,5-trisphosphate (IP3…
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