Proceedings of the National Academy of Sciences, Volume 122, Issue 11, March 2025. SignificanceDuring the nitrogen-fixing symbiosis between the alphaproteobacteriumSinorhizobium melilotiand the plantMedicago sativa(alfalfa), the interplay of molecular mechanisms governing
Proceedings of the National Academy of Sciences, Volume 122, Issue 11, March 2025. SignificanceOur data demonstrate the absence of overt toxicity and the therapeutic efficacy of the specific SOS1 inhibitor
Proceedings of the National Academy of Sciences, Volume 122, Issue 11, March 2025. SignificanceThe brain at rest replays activity patterns observed during task performance, but the function of this replay
Proceedings of the National Academy of Sciences, Volume 122, Issue 11, March 2025. SignificanceCRISPR-based technologies have broadly enabled genome editing over the past decade, however, current approaches are disproportionately based
Proceedings of the National Academy of Sciences, Volume 122, Issue 11, March 2025. SignificanceThe immunological properties of induced pluripotent stem cells (iPSCs) during allogeneic transplantation have not yet been fully
References Rodriguez-Canales, J., Eberle, F. C., Jaffe, E. S. & Emmert-Buck, M. R. Why is it crucial to reintegrate pathology into cancer research? Bioessays 33, 490–498 (2011). Article PubMed PubMed
Data availability Targeted deep sequencing data, whole-transcriptome sequencing data and whole-genome sequencing data can be accessed from the the National Center for Biotechnology Information under BioProjects PRJNA1223321, PRJNA1221787 and PRJNA1221509.
Real-time surveillance of viral genomes enables the detection of new variants, the assessment of their impact on infectivity and disease severity, the estimation of rates of spread and routes of
Bright auroras could be visible tonight (Tuesday) in the Northern U.S. as Earth passes through a corridor of charged particles leaking out of a “coronal hole” in the sun’s atmosphere.
The giant luminous swirl was seen clearly across large parts of England. This striking video was captured from Billingborough, Lincolnshire. (Image credit: Simon Minnican/@minnican.bluesky.social) On Monday (March 24), a giant
