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Now Reading: B cell–derived acetylcholine mitigates skin inflammation in mice through α9 nicotinic acetylcholine receptor–mediated signaling

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B cell–derived acetylcholine mitigates skin inflammation in mice through α9 nicotinic acetylcholine receptor–mediated signaling

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B cell–derived acetylcholine mitigates skin inflammation in mice through α9 nicotinic acetylcholine receptor–mediated signaling

AdminUncategorized2 weeks ago26 Views

Proceedings of the National Academy of Sciences, Volume 122, Issue 17, April 2025.
SignificanceChronic inflammatory skin disorders affect millions worldwide. Our study reveals a role for acetylcholine (ACh), a molecule typically associated with neuronal signaling, in regulating skin health. We demonstrate that B cells produce ACh to …
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