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Now Reading: Conserved C143 forms a branched intermediate in Hedgehog autoprocessing: A cancer drug discovery target against Hedgehog signaling

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Conserved C143 forms a branched intermediate in Hedgehog autoprocessing: A cancer drug discovery target against Hedgehog signaling

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U.S.//Discover the latest updates from across the United States, including politics, culture, economy, and trending stories. Stay informed on the key events shaping the nation and the topics everyone’s talking about.
World//
Opinion//Transform your living spaces with inspiration, tips, and trends in interior design. From minimalist decor to bold statements, find ideas for every style and budget.
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Lifestyle//Explore stories and advice on living your best life. From personal growth to entertainment, dive into the latest in lifestyle trends and inspiration.
Health//Stay informed about health and wellness with expert advice, fitness tips, and the latest medical breakthroughs. Your guide to a healthier and happier life.
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Conserved C143 forms a branched intermediate in Hedgehog autoprocessing: A cancer drug discovery target against Hedgehog signaling

IO_AdminUncategorized1 month ago11 Views

Proceedings of the National Academy of Sciences, Volume 122, Issue 17, April 2025.
SignificanceHedgehog (Hh) signaling plays fundamental roles in embryonic development while its abnormal activation in adults is associated with cancer. Hh-targeting drugs have gained FDA approval, but resistance has emerged quickly, underlining the need …
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