DNA bending mediated by ORC is essential for replication licensing in budding yeast

IO_AdminUncategorized2 months ago30 Views

Proceedings of the National Academy of Sciences, Volume 122, Issue 14, April 2025.
SignificanceThe origin recognition complex (ORC) plays the important role of a replication initiator that binds origin DNA after an elaborate site selection process, and recruits two minichromosome maintenance (MCM) hexameric rings in a head-to-head …
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