The emerging work by City Therapeutics on small cityRNAs represents an advancement in RNA-based therapies, perhaps contributing to the growth of precision medicine globally. For India, this research could offer insights into addressing challenges such as drug-resistant diseases or genetic disorders through innovative applications. Moreover,it highlights the increasing global investment in biotechnology-a sector where India is also aspiring to position itself as a key player. Strategic collaborations with firms like City Therapeutics may amplify India’s biotech industry further and align with its healthcare development aspirations.