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Now Reading: FLIPL permits apoptotic and inflammatory signaling and inhibits necroptosis in mice without Caspase-8 oligomerization

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FLIPL permits apoptotic and inflammatory signaling and inhibits necroptosis in mice without Caspase-8 oligomerization

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FLIPL permits apoptotic and inflammatory signaling and inhibits necroptosis in mice without Caspase-8 oligomerization

AdminUncategorized1 month ago13 Views

Proceedings of the National Academy of Sciences, Volume 122, Issue 15, April 2025.
SignificanceApoptosis involves the activation of enzymes called caspases, which cleave other proteins. One caspase is Caspase-8, which is activated upon ligation of certain receptors. Caspase-8 can promote apoptosis, but it also functions to inhibit …
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