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Now Reading: Inactivation of microglial LXRβ in early postnatal mice impairs microglia homeostasis and causes long-lasting cognitive dysfunction

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Inactivation of microglial LXRβ in early postnatal mice impairs microglia homeostasis and causes long-lasting cognitive dysfunction

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Inactivation of microglial LXRβ in early postnatal mice impairs microglia homeostasis and causes long-lasting cognitive dysfunction

AdminUncategorized1 month ago41 Views

Proceedings of the National Academy of Sciences, Volume 122, Issue 15, April 2025.
SignificanceMicroglia control neuroinflammation by eliminating foreign substances and debris and pruning synapses that affect cognitive function. Our study reveals that early ablation of LXRβ in the postnatal microglia results in a decrease in microglial …
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