# Living review identifies top bipolar disorder treatments 2026-08-13T13:56:13+00:00 | Health & Science | Indian Opinion Desk Corroboration: 1 independent outlet Researchers have published the most comprehensive review of bipolar disorder treatments, covering 77 meta-analyses and 116 interventions. The study, led by The Ottawa Hospital and published in The British Medical Journal, found that for adult bipolar depression, cariprazine, fluoxetine and lurasidone are most effective. For mania in adults, aripiprazole, haloperidol, lithium and risperidone work best. Children and teenagers respond to different drugs, including lurasidone and olanzapine with fluoxetine for depression. The team created an open-access web platform called EBI-BD that shows each treatment's impact, side effects and evidence strength. The review is a 'living review', meaning it updates automatically as new data emerges. Results have already informed guidelines from the International Society for Bipolar Disorders. The tool helps clinicians and patients jointly choose treatments based on individual needs and side-effect profiles. ## Coverage - thehindu.com Tags: bipolar disorder, EBI-BD, evidence-based medicine, living review, medication, mental health Canonical: https://indianopinion.org/living-review-identifies-top-bipolar-disorder-treatments/ License: Summary and commentary (c) Indian Opinion, reusable with attribution. Facts belong to the linked sources. Cite: https://indianopinion.org/living-review-identifies-top-bipolar-disorder-treatments/#story-in-brief Review state: restored archive article, accurate at time of publication, not offered to search indexes.