# LSD-based pill reduces anxiety in late-stage trial, says Definium 2026-08-13T13:56:17+00:00 | Health & Science | Indian Opinion Desk Corroboration: 1 independent outlet Definium Therapeutics said its LSD-based experimental pill, DT120, significantly reduced anxiety symptoms in a 214-patient late-stage trial. Patients with generalised anxiety disorder who received a single 100-microgram dose showed an 11.6-point drop on a standard rating scale at week 12, versus 6.2 points for placebo. The benefit appeared within two days and lasted the full 12 weeks. Side effects were mild to moderate and temporary, with no increase in suicidal thoughts. ## Coverage - thehindu.com Tags: anxiety disorder, clinical trial, Definium Therapeutics, LSD therapy, mental health, psychedelic medicine Canonical: https://indianopinion.org/lsd-based-pill-reduces-anxiety-in-late-stage-trial-says-definium/ License: Summary and commentary (c) Indian Opinion, reusable with attribution. Facts belong to the linked sources. Cite: https://indianopinion.org/lsd-based-pill-reduces-anxiety-in-late-stage-trial-says-definium/#story-in-brief Review state: restored archive article, accurate at time of publication, not offered to search indexes.