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Now Reading: Macrophages release neuraminidase and cleaved calreticulin for programmed cell removal

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Macrophages release neuraminidase and cleaved calreticulin for programmed cell removal

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U.S.//Discover the latest updates from across the United States, including politics, culture, economy, and trending stories. Stay informed on the key events shaping the nation and the topics everyone’s talking about.
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Macrophages release neuraminidase and cleaved calreticulin for programmed cell removal

IO_AdminUncategorizedYesterday4 Views

Proceedings of the National Academy of Sciences, Volume 122, Issue 21, May 2025.
SignificanceThis study provides insights into the mechanisms by which macrophages mark target cells for programmed cell removal (PrCR). We demonstrate that activated macrophages secrete a C-terminally cleaved version of Calreticulin (CALR), which acts as …
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