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Now Reading: MDA5 ISGylation is crucial for immune signaling to control viral replication and pathogenesis

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MDA5 ISGylation is crucial for immune signaling to control viral replication and pathogenesis

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MDA5 ISGylation is crucial for immune signaling to control viral replication and pathogenesis

IO_AdminUncategorized2 months ago30 Views

Proceedings of the National Academy of Sciences, Volume 122, Issue 14, April 2025.
SignificanceThe work by many groups demonstrated the important role of ubiquitination in modulating the activity of innate immune sensors. In contrast, little is still known about the significance of ISGylation in immune receptor regulation…
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