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Now Reading: Mechanism of read-through enhancement by aminoglycosides and mefloquine

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Mechanism of read-through enhancement by aminoglycosides and mefloquine

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Mechanism of read-through enhancement by aminoglycosides and mefloquine

IO_AdminUncategorized4 weeks ago12 Views

Proceedings of the National Academy of Sciences, Volume 122, Issue 17, April 2025.
SignificanceCurrently, genetic diseases caused by mutations that introduce premature stop codons lack effective treatments. Aminoglycosides were the first compounds shown to promote read-through of these stop codons, but their use is limited due to …
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