# Menopause hot flash signals brain change linked to Alzheimer’s

2026-08-10T02:52:45+00:00 | World & Diplomacy | Indian Opinion Desk

Corroboration: 1 independent outlet

A top US professor says the menopausal hot flash is actually a 'brain hot flash' that may signal an increased risk of Alzheimer's disease. Dr Roberta Diaz Brinton of the University of Arizona explains that oestrogen loss during menopause reduces the brain's ability to use glucose for energy by 20-25%, triggering a short-term starvation response. This shift forces the brain to use auxiliary fuels, generating heat that causes the hot flash. Over time, this long-term adaptation can lead to Alzheimer's. Brinton's team is developing a plant-based intervention called phytoserm for hot flashes, aiming to address women's concerns about hormone therapy and breast cancer risk.

## Coverage

- timesnownews.com <https://www.timesnownews.com/health/top-us-professor-reveals-the-brain-changes-during-menopause-linked-to-alzheimers-article-155362260>

Tags: Alzheimer's, brain health, estrogen, hot flash, menopause, US research
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