Modular RNA-Guided DNA Systems Discovered in Prokaryotes and Viruses

Swift Summary

• Researchers explored RNA-guided systems that enable versatile biological functions.
• Using structural and sequence homology-based methods starting with the RNA-interaction domain of Cas9, a new family of RNA-guided DNA-targeting systems was identified.

Indian Opinion Analysis
RNA-guided systems such as those leveraging Cas9 have been integral to advancements in fields like genetics and biotechnology. The advancement or discovery of a new family of RNA-guided DNA-targeting tools could significantly enhance precision in genetic research, benefiting applications from agriculture to medicine in India.For Indian scientists and biotech industries, this represents an opportunity to drive innovation while addressing challenges such as food security and customized therapeutics. India’s robust academic network should prioritize such frontier areas to maintain competitiveness on the global stage.

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