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Now Reading: Mutant IDH1 cooperates with NPM1c or FLT3ITD to drive distinct myeloid diseases and molecular outcomes

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Mutant IDH1 cooperates with NPM1c or FLT3ITD to drive distinct myeloid diseases and molecular outcomes

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U.S.//Discover the latest updates from across the United States, including politics, culture, economy, and trending stories. Stay informed on the key events shaping the nation and the topics everyone’s talking about.
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Mutant IDH1 cooperates with NPM1c or FLT3ITD to drive distinct myeloid diseases and molecular outcomes

kisded kisdedUncategorized2 hours ago2 Views

Proceedings of the National Academy of Sciences, Volume 122, Issue 20, May 2025.
SignificanceOur work highlights the importance of investigating co-occurring driver mutations of a disease and provides a mouse model in whichIdh1mutation, in the presence of mutantNpm1c, is linked to the development of overt AML…
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