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Now Reading: Proofreading and single-molecule sensitivity in T cell receptor signaling by condensate nucleation

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Proofreading and single-molecule sensitivity in T cell receptor signaling by condensate nucleation

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Proofreading and single-molecule sensitivity in T cell receptor signaling by condensate nucleation

IO_AdminUncategorizedYesterday9 Views

Proceedings of the National Academy of Sciences, Volume 122, Issue 22, June 2025.
SignificanceTo fight infections and cancer, T cells must selectively recognize low levels of foreign peptides from pathogens or cancer cells, but the mechanisms that enable these properties remain unclear. Using computational modeling and experiments…
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