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Now Reading: SRP19 and the protein secretion machinery is a targetable vulnerability in cancers with APC loss

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SRP19 and the protein secretion machinery is a targetable vulnerability in cancers with APC loss

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SRP19 and the protein secretion machinery is a targetable vulnerability in cancers with APC loss

AdminUncategorized1 month ago20 Views

Proceedings of the National Academy of Sciences, Volume 122, Issue 15, April 2025.
SignificanceAPCloss is one of the most frequent genetic drivers in colorectal cancer but currently it is not possible to targetAPCloss. Here, we show thatSRP19is codeleted in these cancers and is a unique vulnerability in these cancers…
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