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Now Reading: Structure of the human TWIK-2 potassium channel and its inhibition by pimozide

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Structure of the human TWIK-2 potassium channel and its inhibition by pimozide

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Structure of the human TWIK-2 potassium channel and its inhibition by pimozide

kisded kisdedUncategorized1 week ago11 Views

Proceedings of the National Academy of Sciences, Volume 122, Issue 19, May 2025.
SignificanceThe TWIK-2 potassium channel is a member of the two-pore domain potassium (K2P) channel superfamily and a potential therapeutic target to control severe inflammatory injury involving the NLRP3 inflammasome. We report the cryo-EM structure of …
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