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Now Reading: The cryo-EM structure and physical basis for anesthetic inhibition of the THIK1 K2P channel

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The cryo-EM structure and physical basis for anesthetic inhibition of the THIK1 K2P channel

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The cryo-EM structure and physical basis for anesthetic inhibition of the THIK1 K2P channel

IO_AdminUncategorized1 month ago14 Views

Proceedings of the National Academy of Sciences, Volume 122, Issue 14, April 2025.
SignificanceTHIK1 potassium channel activity controls the function of microglia, immune cells of the central nervous system. As microglia are involved in the pathogenesis of neurodegenerative diseases, THIK1 is an intriguing therapeutic target to modulate …
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