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Now Reading: The highly conserved intron of tyrosine tRNA is critical for m1A58 modification and controls the integrated stress response

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The highly conserved intron of tyrosine tRNA is critical for m1A58 modification and controls the integrated stress response

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The highly conserved intron of tyrosine tRNA is critical for m1A58 modification and controls the integrated stress response

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Proceedings of the National Academy of Sciences, Volume 122, Issue 23, June 2025.
SignificancetRNAs are required to translate the genetic code into protein sequence. tRNAs also contain more modifications than any other RNA. Although tRNA introns are universal in eukaryotes and distinct from other introns, their function has remained …
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