The oncoprotein SET promotes serine-derived one-carbon metabolism by regulating SHMT2 enzymatic activity

IO_AdminUncategorized1 week ago17 Views

Proceedings of the National Academy of Sciences, Volume 122, Issue 19, May 2025.
SignificanceCancer cells change the way they use nutrients to support rapid growth and proliferation. Our study shows that the oncoprotein SE translocation (SET) partners with the metabolic enzyme SHMT2 to enhance serine-derived one-carbon metabolism…
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