Understanding TAK1 deficiency in microglia: Dual mechanisms for photoreceptor protection in a mouse model of retinitis pigmentosa

kisded kisdedUncategorized2 weeks ago11 Views

Proceedings of the National Academy of Sciences, Volume 122, Issue 18, May 2025.
SignificanceWe demonstrated the dual functions of transforming growth factor-beta-activated kinase 1 (TAK1) in microglial-mediated neuroinflammation in the rd10 mouse model of retinitis pigmentosa (RP). Specifically, heterozygous TAK1 deficiency …
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