Now Reading: Living review identifies top bipolar disorder treatments
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Living review identifies top bipolar disorder treatments
Researchers have published the most comprehensive review of bipolar disorder treatments, covering 77 meta-analyses and 116 interventions. The study, led by The Ottawa Hospital and published in The British Medical Journal, found…
The Story in Brief
Researchers have published the most comprehensive review of bipolar disorder treatments, covering 77 meta-analyses and 116 interventions. The study, led by The Ottawa Hospital and published in The British Medical Journal, found that for adult bipolar depression, cariprazine, fluoxetine and lurasidone are most effective. For mania in adults, aripiprazole, haloperidol, lithium and risperidone work best. Children and teenagers respond to different drugs, including lurasidone and olanzapine with fluoxetine for depression.
The team created an open-access web platform called EBI-BD that shows each treatment's impact, side effects and evidence strength. The review is a 'living review', meaning it updates automatically as new data emerges. Results have already informed guidelines from the International Society for Bipolar Disorders. The tool helps clinicians and patients jointly choose treatments based on individual needs and side-effect profiles.
The Indian Opinion
Media coverage may hype this as a magic answer, but the real story is the slow work of matching patients to drugs, not declaring a winner. Ordinary Indians know that one-size-fits-all fixes rarely work for mental health. The EBI-BD platform's value lies not in naming top drugs but in letting doctor and patient weigh side effects together. Watch how many Indian hospitals actually adopt this tool in the next year; that number, not the press release, will tell us whether care is really changing.
Source: thehindu.com
This story was synthesised by AI from the source linked above.
