LSD-based pill reduces anxiety in late-stage trial, says Definium

Definium says LSD-based pill reduces anxiety in late-stage study

Definium Therapeutics said its LSD-based experimental pill, DT120, significantly reduced anxiety symptoms in a 214-patient late-stage trial. Patients with generalised anxiety disorder who received a single 100-microgram dose showed an 11.6-point drop…

The Story in Brief

Definium Therapeutics said its LSD-based experimental pill, DT120, significantly reduced anxiety symptoms in a 214-patient late-stage trial. Patients with generalised anxiety disorder who received a single 100-microgram dose showed an 11.6-point drop on a standard rating scale at week 12, versus 6.2 points for placebo. The benefit appeared within two days and lasted the full 12 weeks. Side effects were mild to moderate and temporary, with no increase in suicidal thoughts.

The Indian Opinion

Psychedelic medicine is shedding its counterculture stigma, but the hype may race ahead of the science. This single-dose pill showed a 5.4-point improvement over placebo on an anxiety scale, a real but modest effect. Wall Street cheered, yet the real test will be long-term safety and whether the benefit holds beyond 12 weeks. For the 26 million Americans with generalised anxiety disorder, a new option is welcome, but let the regulatory review, not share prices, be the judge.


Source: thehindu.com

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